A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response
Keywords: BSO, dl-buthionine-[S,R]-sulfoximine; CsA, cyclosporin A; DHR, dihydrorhodamine 123; GDH, glutamate dehydrogenase; GSHMEE, reduced glutathione monoethyl ester; LDH, lactate dehydrogenase; MPT, mitochondrial permeability transition; PI3K, phosphatidylinosi